Wednesday 30 August 2017

H pylori mode of transmission

Iatrogenic transmission of H. For the general population, the most likely mode of transmission is from person to person , by either the oral-oral route (through vomitus or possibly saliva) or perhaps the fecal-oral route. Helicobacter pylori is found predominantly in human gastric mucosa. Transfer of the bacterium remains an open topic, but it is likely that infection is usually acquired at a young age, particularly where lower socio-economic conditions prevail.


Transmission via an external source such as water supply is a possibility but, in general, infection is probably passed from person to person.

These findings demonstrate the acquisition of H. However, most individuals never develop clinical disease. Thirteen years after the culture of H. Marshall and Warren, we still do not know its major mode of transmission. Childhood represents the major period of acquisition of infection in the third worl but infection is rare in children in the developed world. The gastro-oral route is the typical modality of transmission in the childhoo when H. They have tried to isolate H. In this study we have investigated the possible role of food asreservoir or vehicle in the transmission of H.

Failure to consistently isolate H. Studies showed that H. Presently, interpersonal pathways are more probable than environmental exposure routes. Most infections are acquired in childhood and risk factors associated with childhood infection include poor sanitation, overcrowding and lower socioeconomic status. The route of transmission of H pylori infection has been widely hypothesised but the exact mode (s) of transmission is still unknown. Currently, several routes of transmission have been postulated including oral-oral, faecal-oral, iatrogenic, fomite, and vector borne, but no definite transmission pathway(s) has yet been identified. The possibility that the gastro-oral route may be an important route of transmission of H. For example, an early report postulated that the most likely route of transmission of H. Ingestion of the bacteria, which is the most likely portal of entry, may occur by one or a combination of three means: oral-oral, gastro-oral, or fecal-oral, but determining a dominant route is not an easy task.


The mode of transmission of H. This usually happens during childhood. A common cause of peptic ulcers, H. Its helical shape (from which the genus name, helicobacter, derives) is thought to have evolved in order to penetrate the mucoid lining of the stomach and thereby establish infection. Observations such as these support the hypothesis of person-to-person transmission of H. If close personal contact in transmission of H. The study by Tindberg et al. There is some evidence to suggest that H.

At this stage the oral-oral or faecal-oral transmission routes are the most likely. Although the prevalence of H. Despite intense investigation into the spread of H. Western world is decreasing, gastric colonization by H. A number of studies confirm that H. There have, however, been some interesting papers on the presence of the organism in foo water, and the oral cavity. Typically, the bacteria enter the mouth and work their way into the.


While infections with this strain of bacteria typically don’t cause symptoms, they can lead to diseases in some people, including peptic.

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